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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4401af7e4ca30f830f1edd6760a8df75613427e1f4e228f8a50aee0600ef1213' 
  AND token = '5jLoTtr50o4UZ7owL6SI5iGsm6VvXIASjQZihB0UCSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}