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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d753d4bb524eea65734f44cc22323b7de89007c4c14cad5043d022247357ea8' 
  AND token = 'SzCFiT0Ow1hm2roxBr4NH7LNZSvZgW6w6Qa9O96GTtQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}