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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9259adbf3e907d507e3c2023491b564b200e5905235dc39cc0b6a145de702830' 
  AND token = 'SngcVnIKSJtxghsw+7kizrDz/2P5r33yjzTjiom0Dz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}