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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54f7fe07bd97ff6504dae7fc33f554b386e0c51c763c1a964853031fd70636fb' 
  AND token = 'zDY28R7h8VxRv7vqXR/8npQYrLmuOV3TJQ2Pa1qWVf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}