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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc1d7aaec6f0fa067a1e10436e06f5d08ec3003dfc5466ad94c2beefa4e109df' 
  AND token = 'DfUx0/5je8XP+K1cZU9T+mu9dRXdfhf5x7wHMm1HLFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}