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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46552bba7cedbe1dd264d29452f5fab60d2867560523613843823e2b24e049c5' 
  AND token = '/RC8YU9NkuOrWQeIGP03hgjMhFCmKI7Lz8YLNkrr+KI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}