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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8463d103689c715daf332cf4ab2ef8eb4de192b7282d1e7faa458d4dfc5352a1' 
  AND token = 'SHGFIKqHOwqJX0zeB8D48WynOFtmMZEiRRwn0zlmFi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}