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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b1e34dd8aa3f400802c0e29037ae330d3d931cfb8c6f236f230cb99f3b16d44' 
  AND token = 'TK3N1pTi9cFyiAwG+Y6MnMTmoxIT7z9NVt9/UdiZnms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}