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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36974cdb617a6874f6877301ff544be493d837a5d2a108c39685756182bea299' 
  AND token = 'AN6rHdmlmcOVIwaH4EIXfyUTq8A8eeaZURXXE/aFnSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}