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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4870b863be26d8d5c019559c4c4d220eeb07e786465cd5a78c69723e8680e72' 
  AND token = 'pw6AG6Ita0Y1xfrXQnAOQxYSKQqSeDUUavCCIdCQ4Io=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}