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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50408bd82a979fcb16bd24b6580e4c0bd6316b6deee698b040d58aef09e2b1b1' 
  AND token = 'PLSVjXMIDmmLl6EoPOfYCwp9eeK7HVHE8+Bjibs75C8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}