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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1404dc656015010c28b865a8aab2280e222bc1e9134a635694db9bcdf00f63f9' 
  AND token = 'W+jEVijAFil33sYXGr3hq9m3HDE0gn2VvdaoqpAVccs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}