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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '914d7740a004ea234a407de517cd52b14b1ee512c0c24ff68da7609b2735ee01' 
  AND token = 'Z8zyH4VcF9tVdPLAqX2GPkxuluKkdpCW67rM+1ZzCls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}