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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c68967ec3511f80bf6347152622ac69566bb2b5d50f52c9322e6278d5194c281' 
  AND token = 'J50fQrkBbiIkaGRoYRxzc4oYrfDy3yqgTeqPxGuV+vk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}