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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e614c8ec99ac2483dd43d8caed64cbfed708b55cb1d865e00f8505655e153cd8' 
  AND token = 'p4GtAMadZZvG1zQ+Q1eSLkHOI6oeYFc4csASPaURc7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}