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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b584c370fc691a11180df9580679bd5d37c055459398ee0cd2e705342d8c6f05' 
  AND token = 'E6y5rRnjeiSYPxY4MuX6pXouYE8dxu/pysFsdW4Nz9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}