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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8208c35e33af98325a566d3f1ce0295008d77da5a148b95fc9edd26e20bf6a87' 
  AND token = 'uALz0zQe5sYwnAQgacSdC14KwhzlNCvOgAWC7R9BrAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}