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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46fd7f1896fd6c47d18a68de425af142df6950637b0662692cde4761e42029d4' 
  AND token = 'cAa577xRnRKUXWAQOhoUSk220FFCo/bMwnZF32Zl0Mg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}