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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0df76c82a4c87c8c5cefe3f978b37a919e46d5b5ec6992cdcc27ab5c60d36997' 
  AND token = 'iuM+CcSZ1Tv7RjPKqNYKwCVtqyuiQ9ERd7ACy10ykZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}