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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '073fe03e401ad3d7b4f27db26cd80c7df2720e410a789005ece34fb70bdf49c6' 
  AND token = 'b4PsO5jdtDL/s7oVfL3dp0VZsycMfHlaXC3O9Pibc1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}