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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f12a3f688dae70b56926ac2eef64b733262b54b8711915bed71c32aa8b9985f' 
  AND token = 'ugPfIQQ60vWmgB66QWD+gWuF37UMKmET9/EU3FpC7tM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}