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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ecdf357ca9e6e8be94b3682fcb2089b4304f6d1900419bf59bd9486a2df267f' 
  AND token = 'RWEi85vV4hnUJmdEgkJjbhLrDMjMxIoT21tgSZMJ9f8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}