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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d8cbd053aa800846d4ac1231030730ea5e5e2d7100b7f763a2711b8e7cd3e49' 
  AND token = 'WYFtlEn7jG1f1J+gPmPoBLd4LGCVaPHfR9UW2gpiuKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}