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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1848d185ea55a5dfb20ecdb45ad5e15e52c4fdd355bb5c54801c4a9f68092dae' 
  AND token = 'qAiIH/3EIrKPr8G75xpMJQ3ROKHEOeJ37gi8G+ZZgHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}