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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f106665ed3274b18f5e55afabb7a66fa801c446dd9d4b5b143488a4e2735b065' 
  AND token = '6cnhtpeqtUZN38zP4JDftoHvNCcsRYv1VD47esidMvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}