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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46100afeff8215033ec9ea39e4e93772889404b22f60008d3ad3fbbb902ea2bd' 
  AND token = 'U4K9L0/fPhdM5Q0nnBTMIf++vtv5UfB90piyyrOj9zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}