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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '814ec59984caa7adc35b9ccb155b6c26d4f0454b66f70fffb1b47f139057d4e2' 
  AND token = 'ThXjQM7KVAP//H4A8AdQe5dzv2ehzXcMu9S/NbZfqH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}