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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd48139260f2366e2f105cb250920c6ffb4b7cd9e9fa58a007f44430930b00d3' 
  AND token = '6Ez9o9p2Lnk+7v0rOEMoHB/UXZ6U+WooGzGZoM+B2aA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}