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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '917c4b2286f78351cf750349fa514bc754afd1a76217aabc84972187e1b2673f' 
  AND token = 'I7PBuXNEQYY4xLQ2Tbk/Dy/Dcxe5MCAFmiKZsRcM5Kc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}