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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca7144f90b28d64ca4183d99e9599597892a3aa9c9331819c3c3d62e56bb2e72' 
  AND token = 'Qi/HGIg847AIRZFRlpS/2cNRuM9ukIbCRMC+TeeabNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}