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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '660c26d9dc70ca89a71f128471d5ca492bcbdcaf4aa353032e000ab702190cf5' 
  AND token = '45g5/tutrzmePQM0kz60sO2faB9pHk3OBYLmdMI12bg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}