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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61819f65052181032b525197f03bf4996bc254eba5871c186f5111052dc13328' 
  AND token = 'FtS+80f+/Atq2FXYq2f9pmm0qM4A1IF2QxKtQQ0Ztg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}