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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1383299f30da73363a300675a581e589905d19d89a5f1d8d3e35b24239004265' 
  AND token = 'ZTLz1vzkuTQjUJO8of+x7zC0Qfo3rbGZfCPY0CmnR0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}