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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec0bc4b99412362f6419bf517185ccc8c0091b4fa5944c7d4a30d1cdcc47928f' 
  AND token = 'joveev+0IAbD0EgaQj72/Lz3GO3Bjs7BsXmydKwlqaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}