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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72e46899aeb7a32ba8a85fc7114a455cab216ac485b48b9b4e1bb8f7484ebc97' 
  AND token = 'diZZ6OB68kuogLE/0Rhwxmtn4jPchBSuo1fd/mj2JTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}