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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e6bf36033ae3d6db76075732dc55c6d78695320c0b44061b5e4d199db2aaf7e' 
  AND token = 'jEK+aTN1Q6B2H6ULkXaldFDB2KBOPU1NmmpIoAGxMuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}