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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23e7c52bf25db79156f37d03d2679490bfc856f014b6f0763425861eadcc7043' 
  AND token = 'WtwaCeOTvlCQOMtC7HcfHn/zz5o2nS1G5dcwAY9m5KM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}