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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b051a8d9af1edf3a75ebb56c88a6e01698e0dea2a3b3b54f38d6ae09b9448981' 
  AND token = 'weuQNQCqegtSVGJ1AuDR/6LQ0ZAXUPIqE6kgD5/r7oU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}