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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c7f93cb916bcf05928110c7e9c56ecdf2c2919a13c900ef2f8e3ef07028f340' 
  AND token = 'oL7tINyL2+eDixt6SggMrmi+xRO43dJ0m1aqyNxIxmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}