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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1589452781a58e6e1a4f40aadb1c0b30f77e1b84b5cb16474cd3ccf527c9099' 
  AND token = 'KjLc7wmQfFmOF1M5NX7W3T21tQCkMobwGZceReGcS8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}