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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e372151c826dbf2419af56e69708c3bd4dcf617f11a85ed6e0358197589c1e9f' 
  AND token = 'o/pQwkHifvaoiIVdOT3XQevSiTRaQaanZ5P8NMeyze8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}