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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65a840e4fb4e035a61be04bd911d4cb3e00921a8039d613c6faa1c7e8a7f228d' 
  AND token = 'so+xwldRS1VTTs8bVP4OpgvJr1TCjOlFk7wEQMMT8K8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}