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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '563cbe73451f3e2cb2bf97f7b8f67b8563cd27676759c544fa66bf2b422e262e' 
  AND token = 'BX++qd51klpnNUnwwWaFalMrr72xw1DNlpOCcGRnrzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}