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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd37b6d78be0512837d48e02c04d9845778dcac29e9a9b8aab741d8c12eacb58' 
  AND token = 'xA+PNaFBSFf7mqPnStT6EaPzJ/ge+o+XNzx1au8Af3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}