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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4de396fd7dcd7f85ae90bdf39eb31605af68a07d0c80eebdaf7c187f26c07418' 
  AND token = 'C/2mHaRAQzk9sxkyxMrUAZMs7DGntBA82yGTqxJaC14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}