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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41491e580e5244d0d6a1093d83ce09508d33014dc952ca4dbdc0b437a48483a4' 
  AND token = '/k8s1r+paKU1QTbu7GGtUfKtjuoW7iIqdR7CPiU/tBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}