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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '755ff9e8b614044d7e43232e76963d40d1ee30cc52913bc763a2e48e2244aeee' 
  AND token = 'OqqGym71BhY4TKGnIsg+KGxoDvRrRPZ+R9yERf+/8aQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}