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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a15e58d129f416dee2a12f01ec7621f055876c82070c80b2eb1340ea3db6688' 
  AND token = '3uCZOVUWaoPOTaOYo7sS1fYhLx3mG0/zkSD1b+yTCds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}