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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cb11c0f0f051c80aa1ed7c23b96e572f2f4c729708c5fcc9ba5ff5b9e84e2fc' 
  AND token = 'wRCKQg9JiJ1GwDxysS8KCt7FP1zlFpevxcozL9RZ4Ok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}