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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24deac91ab8fb85a9565d3649f332213ec33021e04d4e574480072bc1d40af18' 
  AND token = 'UfGzYtINwuVK7Xw3GNx6wK0OKwygqnr1Ia6YI/ElEHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}